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High Throughput Screening Methods: Evolution and Refinement, Chapter 12 Small-molecule-mediated Targeted Protein Degradation for Drug Discovery . Rohan E. J. Beckwith
, 2017
, Pages 252-274
Protein–Protein Interaction Regulators, CHAPTER 9 Pharmacological Regulation and Functional Significance of Chromatin Binding by BET Tandem Bromodomains . Michael D. Olp, Huarui Cui, William C. K. Pomerantz, Brian C. Smith
, 2021
, Pages 209-248
Epigenetics for Drug Discovery, CHAPTER 8 Progress in Targeting Epigenetic Readers . Chun-wa Chung
, 2016
, Pages 192-229
Inhibitors of Protein–Protein Interactions: Small Molecules, Peptides and Macrocycles, Chapter 3 The Challenge of Prosecuting Intracellular Protein–Protein Interactions: A Multi-modality Examination of Chemical Matter Identification, Biophysical Characterization, and Membrane Permeability . L. Fan, W. T. McElroy, T. K. Sawyer, P. R. Sheth, D. M. Tellers
, 2021
, Pages 66-110
The Discovery and Utility of Chemical Probes in Target Discovery, CHAPTER 11 Chemical Probes in Cellular Assays for Target Validation and Screening in Neurodegeneration . Ana M. Silva, Anna Cederbalk, Daniel Ebner, Elena Di Daniel
, 2021
, Pages 276-319
Antiviral Discovery for Highly Pathogenic Emerging Viruses, Chapter 1 Overview of Antiviral Drug Discovery and Development: Viral Versus Host Targets . Guangdi Li, Erik De Clercq
, 2022
, Pages 1-27
The Discovery and Utility of Chemical Probes in Target Discovery, CHAPTER 7 Targeted Protein Degradation Chemical Probes . C. Galdeano, X. Barril
, 2021
, Pages 150-181
Protein Degradation with New Chemical Modalities: Successful Strategies in Drug Discovery and Chemical Biology, Chapter 2 Structural and Biophysical Principles of Degrader Ternary Complexes . David Zollman, Alessio Ciulli
, 2020
, Pages 14-54
Protein Degradation with New Chemical Modalities: Successful Strategies in Drug Discovery and Chemical Biology, Chapter 6 Structure-based PROTAC Design . Darryl B. McConnell
, 2020
, Pages 115-134
Epigenetics for Drug Discovery, CHAPTER 12 Safety Considerations for Epigenetic Mechanisms as Drug Targets: Are Existing Toxicology Studies Fit for Purpose? . Paul Butler, Michael Lawton, Robert E. Chapin, Brett D. Hollingshead, Karen Leach, Prashant R. Nambiar, Mathew Pletcher, Amy H. Yang
, 2016
, Pages 288-315