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Potent, selective and cell-permeable inhibitors of protein function ("chemical probes") are valued reagents in both fundamental and applied biological research, and they are essential for the early stages of drug discovery by allowing preclinical target validation in both academic and industrial laboratories.

SGC chemical probes meet the following criteria:

  • In vitro potency of <100 nM
  • >30-fold selectivity vs other subfamilies
  • Demonstration of on-target effect in cells at 1 µM

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Structural Genomics Consortium  


+1 416-946-3795  

 


MaRS Centre, South Tower, 101 College St., Suite 700  

Toronto  

Ontario  

 

Canada 

Biological Properties



 

 

 

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