ChemSpider 2D Image | (S)-MG132 | C26H41N3O5

(S)-MG132

  • Molecular FormulaC26H41N3O5
  • Average mass475.621 Da
  • Monoisotopic mass475.304626 Da
  • ChemSpider ID21467847

  • defined stereocentres - 3 of 3 defined stereocentres

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(S)-MG132
1211877-36-9 [RN]
BENZYL N-[(1S)-3-METHYL-1-{[(1R)-3-METHYL-1-{[(2S)-4-METHYL-1-OXOPENTAN-2-YL]CARBAMOYL}BUTYL]CARBAMOYL}BUTYL]CARBAMATE
D-Leucinamide, N-[(phenylmethoxy)carbonyl]-L-leucyl-N-[(1S)-1-formyl-3-methylbutyl]- [ACD/Index Name]
MFCD28580122
MG-132(R)
N-[(Benzyloxy)carbonyl]-L-leucyl-N-[(2S)-4-methyl-1-oxo-2-pentanyl]-D-leucinamid [German] [ACD/IUPAC Name]
N-[(Benzyloxy)carbonyl]-L-leucyl-N-[(2S)-4-methyl-1-oxo-2-pentanyl]-D-leucinamide [ACD/IUPAC Name]
N-[(Benzyloxy)carbonyl]-L-leucyl-N-[(2S)-4-méthyl-1-oxo-2-pentanyl]-D-leucinamide [French] [ACD/IUPAC Name]
Z-L-Leu-D-Leu-L-Leu-al
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

MG 132 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Bio Activity:

      Enzymes Tocris Bioscience 6033
      Potent 20S proteasome inhibitor Tocris Bioscience 6033
      Potent 20S proteasome inhibitor (IC50 = 0.22 nM). Exhibits cytostatic and cytotoxic effects in tumor cells in vitro. Tocris Bioscience 6033
      Proteases Tocris Bioscience 6033
      Proteasome Tocris Bioscience 6033

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

Density: 1.1±0.1 g/cm3
Boiling Point: 682.0±55.0 °C at 760 mmHg
Vapour Pressure: 0.0±2.1 mmHg at 25°C
Enthalpy of Vaporization: 100.1±3.0 kJ/mol
Flash Point: 366.3±31.5 °C
Index of Refraction: 1.506
Molar Refractivity: 131.8±0.3 cm3
#H bond acceptors: 8
#H bond donors: 3
#Freely Rotating Bonds: 15
#Rule of 5 Violations: 1
ACD/LogP: 5.75
ACD/LogD (pH 5.5): 3.81
ACD/BCF (pH 5.5): 463.77
ACD/KOC (pH 5.5): 2819.31
ACD/LogD (pH 7.4): 3.81
ACD/BCF (pH 7.4): 463.60
ACD/KOC (pH 7.4): 2818.25
Polar Surface Area: 114 Å2
Polarizability: 52.2±0.5 10-24cm3
Surface Tension: 39.6±3.0 dyne/cm
Molar Volume: 443.1±3.0 cm3

Click to predict properties on the Chemicalize site


Advertisement